Hypoxic pulmonary vasoconstriction hpv is a homeostatic mechanism that is intrinsic to the pulmonary vasculature intrapulmonary arteries constrict in response to alveolar hypoxia diverting blood to better oxygenated lung segments thereby optimizing ventilation perfusion matching and systemic oxygen delivery. Buy hypoxic pulmonary vasoconstriction cellular and molecular mechanisms developments in cardiovascular medicine book 252 read books reviews amazoncom. Hypoxic pulmonary vasoconstriction cellular and molecular mechanisms editors view affiliations jason x j yuan book 20 citations 26k downloads part of the developments in cardiovascular medicine book series dicm volume 252 log in to check access buy ebook usd 16900 mechanisms of oxygen sensing in the pulmonary vasculature . This phenomenon is called hypoxic pulmonary vasoconstriction hpv and is responsible for maintaining the ventilation perfusion ratio during localized alveolar hypoxia in disease however global hypoxia results in a detrimental increase in total pulmonary vascular resistance and increased load on the right heart. Complete reference on hypoxic pulmonary vasoconstriction and hypoxia mediated pulmonary hypertension can be utilized by the physician scientist and researcher in the laboratory as both a technical manual and reference designed for clinicians to guide and improve clinical treatment and diagnosis of patients with hypoxia mediated pulmonary vascular disease and right heart failure
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