Introduction the asia pacific primary liver cancer expert apple meeting was first established in 2010 as a consortium of liver cancer specialists including surgeons hepatologists radiologists pathologists and oncologists in the asia pacific region to improve liver cancer management. Background aims hepatocellular carcinoma hcc is the second most common cause of cancer deaths worldwide the global hcc bridge study was a multiregional large scale longitudinal cohort study undertaken to improve understanding of real life management of patients with hcc from diagnosis to death. Pdf a key mission of the asia pacific primary liver cancer expert apple association is to ensure a coherent view for management of hepatocellular find read and cite all the research you . Asia pacific clinical practice guidelines on the management of hepatocellular carcinoma a 2017 update liver cancer is currently the second most common cause of cancer related death worldwide 1 and hepatocellular those who have primary liver cancer 10 in africa and asia where hbv is endemic 60 of hcc is associated. A consensus meeting to develop practice guidelines and to recommend future clinical trials for radiation therapy rt including external beam rt ebrt and selective internal rt sirt in hepatocellular carcinoma hcc was held at the 5th annual meeting of the asia pacific primary liver cancer expert consortium
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